{"id":1394,"date":"2017-04-13T21:12:16","date_gmt":"2017-04-13T15:42:16","guid":{"rendered":"http:\/\/saravanan.org\/?p=1394"},"modified":"2018-07-29T14:44:08","modified_gmt":"2018-07-29T09:14:08","slug":"microbiome-antibiotic-21st-century-diseases","status":"publish","type":"post","link":"https:\/\/saravanan.org\/microbiome-antibiotic-21st-century-diseases\/","title":{"rendered":"Microbiome: Antibiotic for the 21st Century Diseases"},"content":{"rendered":"
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If you haven’t heard the word “microbiome”, this post is going to be the most important thing you read in a long time.<\/p>\n
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I\u00a0am working on creating an enterprise (Food Clinic<\/a>) that will specialize on reversing\/managing chronic diseases using food as\u00a0the 1st medicine.\u00a0Of all the knowledge we are going to use in our practice, the most fascinating and the strangest thing is the knowledge of the friendly micro-organisms that live within, and on, us. These little guys are collectively called our microbiome.<\/p>\n There are five simple things you can do:<\/p>\n Yes! BIG YES!!<\/p>\n Anecdotes from clinics around the world\u00a0have it that patients with multiple sclerosis and chronic fatigue syndrome are getting better, even \u00a0going into complete remission, after a few sessions of FMT!<\/p>\n There is research evidence, though with a small sample size, that FMT from lean individuals to individuals with insulin resistance makes the later become insulin sensitive! Let me translate it for you:<\/p>\n Reversing insulin resistance is a big deal because IR\u00a0often leads to\u00a0heart disease and several cancers.<\/p>\n For other diseases like C. Diff. (Clostridium Defficile) bacterial infection, IBD, Crohn’s, etc., balancing the gut flora, with or without FMT, is the only known possibility of a cure. 85% of C. Diff. infection\u00a0gets cured within hours after an FMT. 95% cases are cured after just to FMT sessions. Other autoimmune disseases don’t have such fantastic success rate. But still, they are impressive.<\/p>\n Incidence of every one of the autoimmune diseases I listed above started to climb around 1950. One number that has been etched in my mind is this: During 1940’s, 1 out of 10,000 American kids was diagnosed to be autistic (we are beginning to suspect that autism is an autoimmune disease). In 2010, the number was\u00a01:68.<\/p>\n Many autoimmune diseases\u00a0started skyrocketing starting 1950s to 1980s.<\/p>\n Several things happened around in the period between\u00a01950 to 1980. They include introduction of certain pesticides to beginning of the usage of high fructose corn syrup.<\/p>\n One thing that seem to play a role in all \u00a0autoimmune diseases is this: \u00a0Antibiotics were introduced in 1944 and their usage exploded from the 50’s. This also includes usage of antibiotics on farm animals. Farmers discovered that when low dose antibiotic was administered to animals every day, they gained significantly more weight. With that, antibiotics were everywhere.<\/p>\n When humans use antibiotics for a long period of time, or if they are exposed to antibiotic while they were still infants\/toddlers, their microbiome gets\u00a0substantially damaged. If they are also on some other medication that can disturb the microbiome (e.g. acid blockers, steroidal medications), things get worse. If this person is a \u00a0picky eater who hates their veggies, or lives in a super-sterile environment that is an antithesis to microbiome diversity, God save them!<\/p>\n Whatever I’ve told you till now is summarized in the pyramid below:<\/p>\n <\/p>\n <\/p>\n Many of your chronic diseases start with bad microbiome (the technical term for this is\u00a0“dysbiosis”).\u00a0Unfortunately, instead of paying attention to the bottom of the pyramid and working on the root cause, we are busy treating the bio-markers (for example, cholesterol and blood sugar numbers). In medical field, it is called “treating the numbers”.<\/p>\n No wonder we have\u00a0no medication to permanently fix any of the chronic\/life-style diseases!<\/p>\n When germ theory was understood, it demystified all the infectious diseases. Germ theory eventually brought us antibiotics, which put an end to infectious diseases. Till then, infectious diseases were periodically wiping\u00a0out a substantial chunk of of human populations.<\/p>\n Take Home 1<\/strong>: Autoimmune diseases, lifestyle diseases and many mental disorders\u00a0that plague us today are loosely called the 21st century diseases. We are beginning to understand that many of them are just one disease: Dysbiosis. With more understanding, treating the 21st century diseases is going to become surprisingly simple and elegant.<\/p>\n Take Home 2<\/strong>: Enriching your\u00a0gut microbiome is a simple, but life-time, endeavor. If you put a little efforts to understand it, you can start enriching your microbiome today!<\/p>\n These books constantly tell you to eat local. There are three reason for this:<\/p>\n So, if you want to tend to the balance of your microbiome, localizing the best practices of the West is extremely important. This includes charting one’s gut microbiome. At Food Clinic<\/a>, we have started to nibble at this problem from the edges. Send us a mail if you\u00a0want to be posted about the exciting developments that are going to come.<\/p>\nFirst, the\u00a0fascinating bits:<\/h3>\n
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What’s in it for you?<\/h3>\n
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How do you re-balance the microbiome?<\/h3>\n
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Does it work?<\/h3>\n
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Autoimmune epidemic<\/h3>\n
Looking in the wrong places<\/h3>\n
Take Home<\/h3>\n
Some interesting books on microbiome<\/h3>\n
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Localizing all this knowledge<\/h3>\n
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