19 Apr

Acid-Blockers Overkill

Acid-Reflux

The current treatment protocol for chronic acid-reflux is a crime. To understand why, you will have to first understand how this disease works.

All posts in this series

Introduction Agents of Dysbiosis

Digestion 101

digestive-tractThe food you swallow travels through a vertical tube called esophagus. Esophagus takes the food into your stomach, where the stomach adds some acid and grinds the food. The acid helps to break down the food and extract nutrients.

After sufficient churning and grinding, the stomach pushes the food into small intestine. As the food travels down the small intestine, more digestion happens. After the food travels some distance in the small intestine, it is mixed with bile which comes from liver (and gall bladder). Bile emulsifies the fat we eat, like soap emulsifies oil, and helps us digest it. Since the bile is alkaline, it neutralizes the acid from the stomach.

In the small intestine, the food is also mixed with various digestive enzymes produced by the pancreas and nutrition extraction happens. After the small intestine is finished digesting the food, the food is moved into our large intestine.

Up until recently, we used to believe that large intestine is largely a waste-bin, holding the digested food till it is excreted. Now we know better. Bacteria living in the large intestine breaks down and eats up our left overs like the fiber that we eat. After the bacteria has done their job, even more energy energy is released (about 30% more) for us to extract from the food.

After the energy extraction, the remaining stuff, with whole lots of stomach bacteria, are stored to be excreted out of the body.

Diaphragm 101

Between our chest and the abdomen, there is a horizontal plane of muscle called the diaphragm. Lungs, heart and esophagus (food pipe) sit above the diaphragm. Stomach, intestines, gall bladder, liver, spleen, pancreas, kidney, urinary tract, etc., sit below the diaphragm.

Diaphragm makes our breathing possible. When we we breath in, the diaphragm moves downward, increasing the volume of our chest cavity. This increases the volume of the lungs, creating a negative pressure inside. Air flows into the lungs to fill it up, creating our in-breathing. When we breath out, the diaphragm moves up, squeezing the lungs and pushing the air out.

Acid Reflux 101

We just saw that the esophagus passes through the diaphragm to reach the stomach. Some of the diaphragm muscle fibers wrap around the esophagus and act like a pinch cock. When you swallow food, the pinch cock opens and allows the food to go down in to the stomach. During other times, it remains closed so that the acidic contents of the stomach don’t escape into the esophagus.

LES-valveThis pinch cock is called the Lower Esophageal Sphincter valve (or LES valve). When it doesn’t work well, acidic content of the stomach flows back into the esophagus. We call this an acid reflux.

Since the esophagus doesn’t have the protective inner lining like stomach, if the acidic stomach contents flow back into the esophagus, the inner surface of the esophagus gets hurt. If the hurt continues for a long time, we are talking years, it might turn into esophageal cancer.

Esophageal cancer is the fastest growing cancer in many parts of the world, including India.

So, there is a sort of compulsion to reduce the damages of long standing acid reflux.

Acid Reflux 201

At times, there is surplus of pressure in/on the stomach which pries open even a normal-strength LES valve and pushes the food back into the esophagus. This is another mechanism through which you might end up getting an acid reflux disease.

Here is the list of all the things that can make the contents of the stomach to flow back into the esophagus:

  1. Weakness in the diaphragmatic muscle fibers make it difficult to keep the LES valve shut
  2. There is a hole in the diaphragm (a hiatus hernia), which makes the LES valve weak
  3. There is too much of food or/and water in the stomach that some of it escapes back into the esophagus
  4. A faulty digestive system and it produces too much of gas and the pressure from the gas pushes open the LES valve
  5. Too much of fat in the stomach (called the visceral fat) leaves too little space for the stomach, squeezing its contents out
  6. Tight clothes like corset put a squeeze on the stomach
  7. Certain food, like fat and caffeine, dilate the LES valve, making it easy for the acidic contents of the stomach to flow back into the esophagus

Let’s see what we can do fix each possible causes of acid reflux.

  1. Weak diaphragmatic muscles: You can strengthen them with breathing exercises. Talk to an yoga teacher.
  2. Hole in the diaphragm (hiatus hernia): Get a surgeon to fix it
  3. Full stomach: Don’t lie down.
  4. Gas in digestive system: This may be caused by the drugs you are taking to reduce your acid reflux symptoms. More about it later.
  5. Too much visceral fat: Lose weight
  6. Tight clothes: Don’t
  7. Some foods dilate the LES valve: Avoid them

Other than these, all backward stretching yoga postures stretch the esophagus. It is believed that with the increased length of esophagus, the lateral pressure on the esophagus increases, shutting it more effectively.

Did you notice that none of the above fixes involve reducing the stomach acid?

Stomach Acid 101

Stomach acid is there for two good reasons:

  • Stomach acid breaks down the food in the stomach, helping us extract protein and other important nutrients. Without sufficient stomach acid, we tend to become malnutritioned.
  • Stomach acid kills most of the pathogens that invade us through the food we eat. Without sufficient stomach acid, we become more susceptible to infections.

Stomach acid is actually a good thing.

SIBO 101

Stomach acid keeps the bacterial content of the stomach acid in check. With weakened stomach acid, there is an over-growth of bacteria in the small intestine. We call this a Small Intestinal Bacterial Overgrowth, or SIBO.

Note: SIBO has many causes. Reduced stomach acid is just one of them.

SIBO has many nasty effects. They include:

  • Nausea
  • Bloating
  • Vomiting
  • Diarrhea
  • Malnutrition
  • Weight loss
  • Joint pain
  • Fatigue
  • Rashes
  • Acne
  • Eczema
  • Asthma
  • Depression

SIBO is also very difficult to treat with antibiotics, with very high rate of recurrence. When a recurrence happens, the symptoms are worse.

Let’s look into on only one ill effect of SIBO: Bloating. The bloating occurs because of improper digestion, particularly food fermentation in the small intestine. The gas generated in the process, which causes the bloating, also causes belching.

When the gas from the small intestine travels to the mouth (assuming that the olfactory senses don’t object to it), it opens up a valve positioned between the small intestine and the stomach (called the pyloric valve) and our friend, the LES valve.

Opening the LES valve, we already saw, causes acid reflux. So, when the stomach acid remains sufficiently low for a long time, we are talking months, SIBO to set in. Once SIBO comes to play, it contributes to acid reflux.

If you already have acid reflux, SIBO makes it worse.

Bile Reflux 101

When the contents of the small intestine open up the pyloric valve and travel into the stomach, some times they carries bile from the small intestine into the stomach.

Again, there are other reasons for a bile reflux. SIBO is just one of them.

When the bile, which is alkaline, enters the stomach, it neutralizes some of the stomach acid, making the problem worse.

Acid Reflux Protocol 101

Now that you have your fundamentals, let me take you to the meat of this post: If you have acid reflux and go to a doctor, what do they do? They give you acid-blockers! So that when the stomach contents flow back, your esophagus isn’t burnt the way it used to be. Let me paraphrase that:

Acid-blockers don’t stop the reflux. It simply stops the acid.

Acid blockers, when taken for a long period of time, give you malnutrition, start SIBO and make the acid reflux symptoms worse. Acid blockers turn evil when the treatment runs into months and years.

Pepsin 101

Here is something that no one probably told you about:

If you have acid reflux, the real damage to the esophagus is done by the pepsin that comes from the stomach!

Pepsin is a molecule that is used by the stomach to digest the protein we eat. But pepsin becomes active only in the presence of acid. When you have a reflux, along with the rest of the food contents and acid, even pepsin rises into the esophagus. When the reflux subsides, some of the pepsin hangs around on the walls of the stomach and lies dormant.

Since you now already have pepsin on the esophageal walls, if you happen to eat acidic food or drink acidic drinks, the acid in your food wakes up the pepsin and it starts to digesting your esophagus. Acid reflux is more about pepsin eating into your esophagus and less about the acid burn.

Let me repeat it:

Acid reflux is more about pepsin eating into your esophagus and less about the acid burn.

To reduce the reactivation of pepsin, you have to be careful not to eat or drink acidic foot.

pH 101

When it comes eating less acidic food, how much is too much?

The acidity of substance is measured on a pH scale. pH “0” is very acidic (battery acid). pH 14 is very alkaline (drain cleaner). Lastly, pH is a log scale. “pH 0” is…

  • 10 times more acidic than pH 1
  • 100 times more acidic than pH 2
  • 1,000 times more acidic than pH 3
  • 10,000 times more acidic than pH 4
  • 100,000 times more acidic than pH 5
  • 1,000,000 times more acidic than pH 6

Now that you understand the pH scale, here is something you are never going to forget:

  • Water is pH 7.0 (neutral)
  • Milk is about pH 6.8 (coconut and soy milk are round about similar value), almost as good as water
  • Coffee is about 5.5, a share more acidic than water
  • Coke and Pepsi are pH 2.5
  • The stomach acid is pH 2

Coke and Pepsi are almost as acidic as the stomach acid. So are many packaged drinks that we use every day.

If you drink acidic drinks or eat acidic food after you have had a reflux, the residual pepsin lingering in your esophagus will get reactivated and start gnawing into the esophageal tissue.

High pH Diet 101

If you are suffering from acid reflux, high the pH of the food you eat lesser you activate the pepsin clinging on to your esophagus.

If you have acid reflux, start eating food that has higher pH value than 5. Do this for two weeks and then stick to pH 4+ food for rest of you life.

With this, about 1/3rd of the people with acid reflux can wean themselves off acid-blocking medication. What more, to keep the pH as high as possible, you will end up eating large quantities of high fiber vegetables, which are excellent for your gut microbiome. So, when you are on high pH diet, you can effectively rule out SIBO.

About 1/3rd of the people with acid reflux can manage with high pH diet and medical intervention. However, the rest 1/3rd typically need surgical correction of their LES valve.

Plug: Food Clinic   has been advising patients on high pH Indian cuisine for controlling their acid reflux.

Criminology 101

I started this post with the sensational claim that current standard protocol for “treating” acid reflux disease is a crime. Now that you have the complete picture, are in a better position to understand why:

  • About 1/3rd  of acid reflux patients can manage their disease with high pH diet. But with the exception of just one organization (Food Clinic) in this country, no one else is even talking about it.
  • About 1/3rd  of acid reflux patients cannot be cured without a surgery. But most of the chronic acid reflux patients don’t even know that there is permanent fix for their problem in the form of a quick surgery.
  • Many patients are not educated about the damage they are doing to themselves by taking acid blocking drugs on the long run.
  • Very few acid reflux patients  have even heard of SIBO, that it has probably been started by their acid blocking drug, that it is going to be difficult to get rid of it using conventional treatment (i.e. antibiotics) and that it is making their acid reflux worse.

Whoever perpetuates this broken system, in my humble opinion, is committing a crime.

Dysbiosis 101

We already saw that prolonged usage of acid blocking drugs damages the gut bacteria balance, resulting in Small Intestinal Bacterial Overgrowth. Often, these patients are put on antibiotics to get rid of their SIBO. If these things mess up the microbiome so the person starts have symptoms of autoimmune diseases like IBS, allergies, etc., they are also put on steroids to lower the immune response.

This is a deadly cocktail designed for disastrous dysbiosis.

Unless someone wakes up to this and starts to work on re-balancing the gut microbiome, this patient will never become healthy again. Ever.

All posts in this series

Introduction Agents of Dysbiosis

 

18 Apr

Antibiotic Overkill

Medicinal Overkill

If you haven’t learned about the antibiotic-over-medication disaster we are in the middle of, it is about time you did.

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Introduction Agents of Dysbiosis

Somewhere from the 1950s, incidents of several autoimmune diseases in the US started growing steadily. That is also when an uptick in obesity and autism was first observed. After much of research, the most probable suspect seem to be this:

In 1944, the world started using antibiotics.

Antibiotics

Antibiotics are drugs that are used to kill disease causing bacteria. Often, they end up killing the friendly bacteria that live in us too.

Before antibiotics came alone, the micro-organisms, including bacteria, were felling populations like fleas. Here is some statistics that will freeze your blood:

  • 30% of the population killed by Antonine Plauge (AD 165-180)
  • 40% of the population killed by Plague of Justinian (AD 541-542)
  • 60% of the population killed by Black Death (AD 1346-1350)
  • 80% of the population killed by Cocoliztli (AD 1545-1548)
  • 50% of the population killed by Cololiztli (AD 1576)
  • 90% of the population killed byUnknown disease outbreak (AD 1616-1619)
  • 75 million people killed by worldwide flu epidemic (AD 1918)

Note: See this Wikipedia page for more details

Compare that with the worldwide flue outbreak in 2009, which was worst we have had in the 21st century so far. It killed 14,286 people, according to Wikipedia (or 18,500 people according to this CNN page). Media, and us, couldn’t stop talking about it when it happened.

Antibiotics was a blessing to the entire human race. Without antibiotics we would have lost many more Srinivasa Ramanujans to the lowly bacteria  (we watched helplessly as Ramanujan’s body and brain was being eaten away by tuberculosis bacteria). And the humankind would have never made the kind of progress that we made in the last 75 years.

Antibiotic Overkill

But there is a dark side to antibiotics that we are beginning to understand only now: Prolonged exposure to antibiotics, or even relatively brief exposure during the childhood, permanently damages the diversity of the bacteria living in our gut.

When we lose diversity of the gut bacteria, chances are that the population of pathogenic bacteria increases.

Whenever the body senses the presence of harmful bacteria in the gut, the gut walls open, rush water into the intestine and flush its content out. We call this diarrhea. Diarrhea is the body’s attempt to flush out the toxic contents of the intestine.

When the toxins or harmful bacteria in the gut are present in large quantities, full blown diarrhea occurs. When these insults are present in smaller quantities, the gut opens up just a tiny bit. Through these slivers, the harmful content of the intestine (pathogens, toxic chemicals, food particles) escape into the bloodstream. Our immune system picks up on the intruders in the bloodstream and starts attacking them.

When these minor insults are caused by what we eat on a regular basis, or how we live, or what kind of bacteria we harbor in our stomach, the insults never end. With the intruders being present all the time, the immune system gets into overdrive.

When the overactive immune system attacks our own body tissue, we call it an autoimmune disease. Depending upon where or how the immune system attacks our body, the symptoms vary from asthma to allergy to irritable bowl syndrome to whole lots of other things.

Many of these autoimmune diseases reverse when the gut microbiome is re-balanced.

Unfortunately, in some cases like with Type-1 diabetes or autism, autoimmune disease causes irreversible damage.

What Should You Do

Here are some things you can/must do to protect yourselves from antibiotic overkill:

  • Take antibiotics only when your life depends on it.
  • This is more for kids:
    • Their microbiome is under developed. So, they are more susciptible for damage.
    • If you damage the microbiome of infants and toddlers, there is not much you can do to restore it
    • Damaged microbiome in infants and toddlers can result in irreversible disaster situations like Type-1 diabetes or autism.
  • If you must take antibiotics
    • Ensure that you combine it with a “good” probiotics. Stagger the probiotics and antibiotic. Otherwise, the antibiotic will kill all the good bacteria in the probiotics.
    • Ask your doctor to prescribe you narrow-spectrum antibiotic that acts on your particular villain, rather than the broad spectrum antibiotic that nukes every bacteria at sight.
  • At the earliest you can, start eating a diet that is friendly to the beneficial microbiome. If the damage to your gut flora is extensive, I suggest you take help from someone like Food Clinic to tweak your diet right.
  • Understand that some diseases for which doctors prescribe antibiotics are made worse by, well, taking antibiotics! Examples are
    • Clostrodium Difficile infection
    • Presistant Acne
  • Be dirty, but in a healthy way (whatever that is)

What Else Should You be Watchful Of

Antibiotic usage becomes particularly destructive on your gut bacteria if you are already doing something that makes your microbiome fragile and vulnerable. Some of them are:

  • You have been on acid blocking drugs for a long time
  • You have been on some steroid medication for a long time
  • You have not been feeding the good bacteria in your stomach
  • You were being too much of a hygiene Nazi

All posts in this series

Introduction Agents of Dysbiosis

 

13 Apr

Microbiome: Antibiotic for the 21st Century Diseases

Gut-Microbes

If you haven’t heard the word “microbiome”, this post is going to be the most important thing you read in a long time.

All posts in this series

Introduction Agents of Dysbiosis

I am working on creating an enterprise (Food Clinic) that will specialize on reversing/managing chronic diseases using food as the 1st medicine. Of all the knowledge we are going to use in our practice, the most fascinating and the strangest thing is the knowledge of the friendly micro-organisms that live within, and on, us. These little guys are collectively called our microbiome.

First, the fascinating bits:

  • The number of micro-organism cells we food and shelter is 10 times more than our own cells.
  • These microbes take active part in running our bodies. They even train our immune system and switch on and off our genes.
  • After our stomach and small intestine extract energy and nutrition from the food we eat, the microbes digest the leftovers in the large intestine, producing even more energy and nutrients for us.
  • The large intestine is not just a waste-bin like we were told in our schools.

What’s in it for you?

  • If you eat the food that is eaten by the good microbes in your gut, all good things happen to you. When you avoid feeding the good microbes, they die out and the gut gets crowded by the bad microbes. Then the hell breaks loose.
  • More precisely, the gut lining breaks loose and lets undesirable things from inside of the gut (e.g. toxic chemicals, food fragments, pathogens) to escape into the blood stream.
  • When that happens,
    • The toxins in the blood cause inflammation all over the body
    • The immune system over-reacts to the inflammation
  • When the immune system overacts, you get auto-immune diseases like
    • Allergies
    • Arthritis
    • Asthma
    • Chronic Fatigue Syndrome
    • Eczema and psoriasis
    • Lupus
    • Irritable Bowl Syndrome
    • Crohn’s Disease
    • Insulin Resistance
    • Multiple Sclerosis
    • Obesity
    • And more
  • Till date, there are no reliable cures for any of these diseases.
  • But now, it is beginning to look like all these autoimmune diseases can be reversed by re-balancing the gut microbiome!
  • How come? If you remember, there is mounting evidence that most auto-immune diseases start with imbalance in the microbiome.
  • There are exceptions. Certain type of autoimmune diseases damage the body irreversibly. They don’t get better by re-balaning gut microbiome. Examples are Type-1 diabetes and autism.

How do you re-balance the microbiome?

There are five simple things you can do:

  1. Eat right: Eat stuff that the your good bacteria likes (fiber, sulfur, fermented food, etc.). These are also called prebiotics. Also, avoid sugar, simple carbohydrates, red meat and high fat diet (personally, I am not convinced about avoiding high-fat).
  2. Probiotics: Only if it is industrial strength and only if you take it for several months or years. Which, to the best of my knowledge, are not available in India.
  3. Medicines on the negative list: Unless your life depends on it, avoid antibiotics, long exposure to acid reducing medication, steroidal medication and toxin filled cosmetics. When you use these medication on kids, the effect is even more pronounced.
  4. Stay dirty: Be less clean. Play in the dirt. Don’t use anti-bacterial wipes. Bath less often (ahem). Don’t use mouth wash (ahem, ahem). Don’t use alcohol based perfumes (ahemn)
  5. Fecal Material Transplant (FMT): This is a stylish way of saying that the excretion of a healthy human being is pushed into the rectum of someone with poor gut microbiome. The material is held within the abdomen of the patient for an hour or so, and then pushed out. The process transfers microbiome of the healthy individuals to the unhealthy one.

Does it work?

Yes! BIG YES!!

Anecdotes from clinics around the world have it that patients with multiple sclerosis and chronic fatigue syndrome are getting better, even  going into complete remission, after a few sessions of FMT!

There is research evidence, though with a small sample size, that FMT from lean individuals to individuals with insulin resistance makes the later become insulin sensitive! Let me translate it for you:

  • FMT can reverse diabetes
  • Diabetes is probably a disease of the gut

Reversing insulin resistance is a big deal because IR often leads to heart disease and several cancers.

For other diseases like C. Diff. (Clostridium Defficile) bacterial infection, IBD, Crohn’s, etc., balancing the gut flora, with or without FMT, is the only known possibility of a cure. 85% of C. Diff. infection gets cured within hours after an FMT. 95% cases are cured after just to FMT sessions. Other autoimmune disseases don’t have such fantastic success rate. But still, they are impressive.

Autoimmune epidemic

Incidence of every one of the autoimmune diseases I listed above started to climb around 1950. One number that has been etched in my mind is this: During 1940’s, 1 out of 10,000 American kids was diagnosed to be autistic (we are beginning to suspect that autism is an autoimmune disease). In 2010, the number was 1:68.

Many autoimmune diseases started skyrocketing starting 1950s to 1980s.

Several things happened around in the period between 1950 to 1980. They include introduction of certain pesticides to beginning of the usage of high fructose corn syrup.

One thing that seem to play a role in all  autoimmune diseases is this:  Antibiotics were introduced in 1944 and their usage exploded from the 50’s. This also includes usage of antibiotics on farm animals. Farmers discovered that when low dose antibiotic was administered to animals every day, they gained significantly more weight. With that, antibiotics were everywhere.

When humans use antibiotics for a long period of time, or if they are exposed to antibiotic while they were still infants/toddlers, their microbiome gets substantially damaged. If they are also on some other medication that can disturb the microbiome (e.g. acid blockers, steroidal medications), things get worse. If this person is a  picky eater who hates their veggies, or lives in a super-sterile environment that is an antithesis to microbiome diversity, God save them!

Looking in the wrong places

Whatever I’ve told you till now is summarized in the pyramid below:

 

Many of your chronic diseases start with bad microbiome (the technical term for this is “dysbiosis”). Unfortunately, instead of paying attention to the bottom of the pyramid and working on the root cause, we are busy treating the bio-markers (for example, cholesterol and blood sugar numbers). In medical field, it is called “treating the numbers”.

No wonder we have no medication to permanently fix any of the chronic/life-style diseases!

Take Home

When germ theory was understood, it demystified all the infectious diseases. Germ theory eventually brought us antibiotics, which put an end to infectious diseases. Till then, infectious diseases were periodically wiping out a substantial chunk of of human populations.

Take Home 1: Autoimmune diseases, lifestyle diseases and many mental disorders that plague us today are loosely called the 21st century diseases. We are beginning to understand that many of them are just one disease: Dysbiosis. With more understanding, treating the 21st century diseases is going to become surprisingly simple and elegant.

Take Home 2: Enriching your gut microbiome is a simple, but life-time, endeavor. If you put a little efforts to understand it, you can start enriching your microbiome today!

Some interesting books on microbiome

  • 10% Human (this is an intense book; but it’ll give you a nice foundation)
  • The Microbiome Solution (for the practical person, with oodles of how-to instructions)
  • Eat Dirt (five types of leaky gut and treatment for each one of them)
  • Brain Maker (effect of gut microbiome on the brain)

Localizing all this knowledge

These books constantly tell you to eat local. There are three reason for this:

  1. Local food is fresh. Processed food is nutrition depleted, sterile and destroys gut microbiome diversity. Though we don’t eat much of processed food in India, if we can eat food within few hours of farming, it brings us additional nutrition.
  2. Locally grown food, provided you live close to a place where your ancestors  evolved, must have evolved along with you. So, it must be more friendly to your guts.
  3. For a similar reason, local microbes are thought to be better than microbes that are shipped from far away land.

So, if you want to tend to the balance of your microbiome, localizing the best practices of the West is extremely important. This includes charting one’s gut microbiome. At Food Clinic, we have started to nibble at this problem from the edges. Send us a mail if you want to be posted about the exciting developments that are going to come.

All posts in this series

Introduction Agents of Dysbiosis

 

09 Apr

The Neuroscience Pyramid

Deconstructing Neuroscience

For a few years ago, I read nothing but books on brain science. I have an unique brain that works nothing like normal brains. The key to getting control of my life depended on my understanding my own brain. With time, I graduated to reading neuroscience books written for medical professionals. From there, reading medical books on other organs was just a hop.

When I got an opportunity to work on healthcare a couple of years ago, I took it up with great gusto. It as an opportunity to bring to practice several elegant solutions that I know are available, but for some mysterious reason, hardly anyone practices. But it is easy to underestimate the inertia of medical industry.

Things got a interesting a couple of months ago: I co-founded an organization called Chennai Neuroscience Foundation, which works exclusively on neuroscience. Though I would loved to have started with biohacking and cognitive enhancement, the business compulsions have it that we start from the exact opposite end.

 

Neuroscience Pyramid

When building the business model for CNS, I realized that the entire neuroscience industry falls into a four layered pyramid

 

4-layers-of-neuroscience-pyramid

Bottom-most Layer: Neurosurgeons and Neurologists work on anything that goes wrong with the tissue of the central nervous system and its blood supply.

Second Layer from Bottom: Cells of the central nervous system communicate by exchanging electrical signals and chemicals. When the brain chemicals (called neurotransmitters) go out of balance, behavior issues like ADHD, OCD, Schizophrenia, Depression, etc., come popping up. A psychiatrist works on the brain chemicals. They try to balance the neurotransmitters as a means of curing us of mental diseases.

Though the electrical signal exchange is crucial for the function of the brain, we don’t understand it well. No medical specialty works on brain electrics. You might just find few doctors and non-doctors dabbling with brain electrics. The days of neuro-electric field is firmly in the future.

Second Layer from Top: Host of other professionals like psychologists, trainers, teachers, coaches, etc., work on the information content of the central nervous system. The information content include memory, fears, addiction, behavior, habit forming, creativity, logical reasoning, muscle memory, etc. Despite 100 years of psychoanalysis, there is much garbage to be thrown out. Novel techniques (like NLP and psychotropics aided psychoanalysis) are taking the pants off from archaic work horses like CBT. This layer of neuroscience is in for a major reboot.

Top-most Layer: The top layer of neuroscience pyramid, the wellness space, is where the charlatans and pseudoscientists roam. This is the least understood part of neuroscience, though it is going to create super-humans out us. Today, there is enough evidence based science out there to make some feeble attempts at neuro-protection and cognitive enhancement. Though it is not much, anything is better than nothing that we had  until now.

 

Education and Training

The deeper you go down the layers of the pyramid, the more education and training the professionals need.

  • A Neurosurgeon, for example, needs 20 to 25 years of formal education, if not more. After this, they undergo 5 to 10 years of in-field training before they reach a decent level of proficiency.
  • A Neurologist, the doctors who work on tissues using pharmacology, goes through similar amount of formal training. Bu their in-field training is shorter.
  • The formal training required for a psychiatrist is very similar to the training required by a Neurologist. However, their in-field training is even less demanding.
  • A psychologist goes through shorter formal education, with a less demanding curriculum.
  • Trainers, Coaches and the like are often made up of people who jump into the field as an after thought. I am yet to come across a kid who dreams of becoming a trainer or a coach when they grew up.
  • All that a neuro-wellness professional needs is a self-certification. As of today, the neuro-wellness field is full of amatuers and snake oil salesmen.

 

Sickness vs Wellness

As you go deeper down the neuroscience pyramid, the sicker the patients must be. And their sickness is more tangible.

Whereas, the customers on the wellness layer shouldn’t even be called a patient. They are already in their pink of health and they are looking for making themselves healthier.

 

Potential of Each Layer

All the life threatening conditions are addressed by the professional operating at the bottom most layer of the neuroscience pyramid.

The challenge faced by professionals operating higher up the neuroscience pyramid is with recovering the potential lost to mental health issues.

But the highest layers of neuroscience pyramid have the capacity to release immense human potential like we have never seen. At least, that is what we technology-optimists believe.

Today, economic activities in neuroscience industry are limited to the lower layers.

In the future, the neuro-wellness industry will grow to be worth several billions of dollars. By then, all the most exciting things on earth will happen in neuro-wellness industry. I am hoping that the business I’ve started in neuroscience industry, CNS Foundation, will eventually take me there.

A guy can hope, can’t he!